View Full Version : Study Suggests Astaxanthin May Protect Against Alzheimer's

12-06-2013, 12:43 AM
We started selling Astaxanthin on our SeaChange site after a study indicated that it was also helpful for lung disease. Now, this report has come out indicating it may help protect against Alzheimer's.


Lee Swanson Research Update
Study Suggests Astaxanthin May Protect Against Alzheimer's
December 5, 2013

New research from Japan suggests astaxanthin may help protect against the development of Alzheimer’s disease. The research centers on the role of the activity of beta-amyloid, a type of protein that accumulates in the brain of Alzheimer’s patients. While the association between beta-amyloid in the brain and the development of Alzheimer’s is widely recognized, the relationship between Alzheimer’s and plasma and red blood cell beta-amyloid concentrations is not well understood. It is believed that beta-amyloid inhibits the ability of red blood cells to deliver oxygen to the brain, in part by inducing oxidative damage to cell membranes.

To explore the association between Alzheimer’s disease and blood beta-amyloid levels, researchers at Tohoku University in Sendai, Japan, examined plasma and red blood cell beta-amyloid concentrations in elderly and younger subjects as well as levels of phospholipid hydroperoxides (PLOOH), a marker of oxidative injury to red blood cells. In a separate experiment, the researchers assessed the effect of two different dosages of astaxanthin (6 mg and 12 mg, once per day, after breakfast) on PLOOH and plasma and red blood cell beta amyloid concentrations in 30 healthy subjects between 50 and 69 years of age.

Compared with younger subjects, elderly subjects had higher plasma and red blood cell beta-amyloid concentrations, as well as higher PLOOH levels. Although astaxanthin supplementation did not affect plasma beta-amyloid levels, it was associated with significant decreases in red blood cell beta-amyloid concentrations and PLOOH levels. Based on these findings, researchers are currently investigating the therapeutic potential of astaxanthin as an anti-dementia agent and expect to present the results of these studies in the near future.

Kiko T, Nakagawa K,et al. Amyloid β levels in human red blood cells. PLoS One. 2012;7(11):e49620. doi: 10.1371/journal.pone.0049620. Epub 2012 Nov 15.