View Full Version : Stem Cell Treatment in Colorado
01-29-2008, 06:40 PM
I've just joined and have browsed here with great interest. I offer below some information regarding a stem cell possibility in Colorado I recently came across. I haven't contacted them myself yet, but do intend to....
"Startup tries stem cells instead of joint replacements"
Denver Business Journal - by Bob Mook Denver Business Journal
by Jim J. Narcy
Regenerative Sciences Inc. has developed a stem-cell procedure that may be an alternative to replacement surgery -- or living with pain -- for those who suffer from knee, hip, elbow or shoulder problems.
The small, Westminster-based company recently launched a patent-pending process called Regenexx, which uses a patient's own stem cells to regenerate bone and cartilage.
In the simple "needle-in, needle-out" process, stem cells are drawn from a patient's marrow, cultivated in a laboratory for two to three weeks and injected back into the damaged area.
Dr. Chris Centeno -- founder, inventor and medical director of Regenerative Sciences -- said that unlike joint-replacement procedures that require weeks of physical therapy and pain medications, patients who go through the Regenexx procedure are back on their feet within one day.
Centeno said the idea behind the procedure came from years of personal frustration as a pain-management physician who deals with patients struggling with joint discomfort.
Regenexx didn't need approval from the Food and Drug Administration (FDA) because it's a medical procedure that doesn't involve medical products, Centeno said. He added that Regenerative Sciences has authored five reports that are being evaluated by peer-review boards.
The procedure, which is available through his Denver practice, has been used on about 50 people in the last two years.
Centeno said seven of 10 patients who went through the procedure reported increased function and dramatic reductions in pain. Centeno said the company is making alterations to the process to improve the results.
Costs for the procedure, which isn't covered by insurance, range from $5,000 to $7,000.
Regenerative Science wants to license the process throughout the country.
Centeno said the company is in negotiations with orthopedic surgery groups in South Florida and Texas. The company also plans to open several small laboratories throughout the country.
A specialist in musculoskeletal, spinal and neurologic injury, Centeno said health insurance companies eventually will cover Regenexx because the process is potentially much cheaper than surgical alternatives. Indeed, Centeno claims that procedures such as Regenexx are the wave of the future.
"You're going to see a lot less major surgeries and a lot more needle-based, low-intervention procedures," he said. Centeno said coronary bypass surgeries have declined 90 percent in the past 15 years. In recent years, doctors have used cardiac catheterization to get inside coronary arteries as an option to invasive surgery. "Everything is done with X-rays and stents," he said.
Regenerative Sciences plans to market Regenexx directly to consumers through advertising -- an approach that's become controversial in medical circles.
"As a doctor, I found it frustrating at first," Centeno said of advertising procedures and medication. "Oftentimes, patients knew more than I did. But I've come to embrace it."
Pixie Greenmeier, a nurse at The Children's Hospital, said the Regenexx procedure worked for her. Greenmeier, 47, underwent the procedure last January to repair a damaged knee. "I couldn't get up without grabbing onto something else," she said. "Now I can get up from a squat." Greenmeier said a grant covered the cost of her Regenexx procedure and her insurance company paid for the lab work.
Regenerative Sciences has raised about $1.7 million in financing since it was founded two years ago.
Besides Centeno, other owners include Dr. John Schultz (who practices anesthesiology and pain medicine in Greenwood Village), John Kisiday, assistant professor of equine orthopedic research at Colorado State University, and Matt Fulton, former CEO of Saint Anthony Hospitals.
All contents of this site ? American City Business Journals Inc. All rights reserved."
For What It's Worth...
01-29-2008, 10:06 PM
Yorkere - Do you suffer from an orthopedic condition? I know this was pretty exciting news when I first heard about it and I would be very interested in hearing how your experience goes if you decide to have treatment there.
01-29-2008, 11:33 PM
Yes; I am currently afflicted with "bilateral glenohumeral osteoarthritis". My left shoulder is the worst; neither has any articular cartilage left, and the left humeral condyle is flat vice rounded, while the glenoid (socket) is badly damaged. Shoulder surgeries are HORRIBLE (try http://www.shoulder1.com) and I'm rather frantically seeking a way out...
On this company's Web site they provide a short summarry of a shoulder arthritis case, but the MRI's shown only display an improvement in the presence of synovial fluid in the "after" shot, NOT any indications of bone structure remodelling toward normal...
And so here's the caveat: Until you can SEE X-rays which CLEARLY indicate that before-and-after changes have definitely occured, use great CAUTION in becoming overly enthusiastic about this stuff...
There is a California company called "Vet-Stem" which has been using autologous stem cell therapy on horses and dogs for some time now, with apparently rather astonishing success (http://www.vetstem.com, I think).
I think I'll give regenexx.com a call in a few days; if it really sounds promising it'll be worthwhile to make a consultation appointment...
01-30-2008, 10:58 AM
I think it would be an excellent idea to contact them for a consultation. That's how you are going to find out answers to your questions. Your condition sounds very painful and serious and I hope that you are soon to find an answer. If the animals are doing well, then it may be the same for humans. I am really excited to hear from you after you contact the clinic. If you need me to go check it out, I will be more than happy to make the drive. I think with the athletes they are getting as clients that the clinic is having good success and has a good reputation.
01-30-2008, 05:51 PM
Thank you so much for your concern toward me; I do believe that some powerful benefits are being realized at this time with stem cells protocols, it's just that without the provision of some forms of visual verification, that great care needs to be taken. People who are desperate for real help are vulnerable to gullibility in these matters...
You mention that you might be able to check them out. Do you live in their vicinity? Are there any others on this List who have displayed any interest in this (I haven't seen ANY posts from anyone else yet)?
Apparently you are a founder of this Web site, have you gone through any such therapy yourself?
01-30-2008, 08:02 PM
I live in Denver so the Colorado clinic is not that far from me. I had umbilical cord stem cell therapy for COPD last April with Jeannine. My son gave us the forum, we wrote a book and we continue to be the best of friends. Getting therapy on the same day sort of bonds you for life. We were the first two to have therapy for COPD at the clinic we went to. You can tell the people on the forum that have had treatment. Under their name on the bottom of their posts, it will say when they had stem cell therapy. I do believe the Colorado clinic is very genuine. As I mentioned, they have some prestigious athletic clients. I was invited to come see the clinic when I first found out about it and called them. They were very friendly and seemed thoroughly sincere in wanting to help people with orthopedic problems.
01-30-2008, 09:46 PM
Thanks for this fast reply! I am very impressed by the e-mails I get notifying me of responses; I just discovered this can be automated. I admire guys such as your son, who know how to set these Web sites up and functioning so flawlessly!
I was not aware you had been familiar with Regenexx prior to my posting, to the extent that you knew of some of their clients...
I filled out the "contact" form on their Web site a few days ago, and received an automated reply stating they would contact me within 36 hours, but haven't seen or heard anything from them yet. Think I'll just give 'em a call rather than wait for them to contact me.
Have you experienced any changes for the better since you had your treatment? I would imagine that the mode of delivery would necessarily be quite different from my situation....for COPD I would expect a spray effect of the stem cells directly into the lungs, whereas in my case it would consist of direct intra articular injection. The current difficulty with these approaches is to keep these cells clustered closely to the sites of interest; I have found some very interesting abstracts which describe various approaches to achieving that....some of this stuff is amazing...One of the difficulties with osteoarthritis is the presence of "eburnated" bone, which is a polished layer of non-viable, eggshell thin bone that resides on the de-cartilaged surfaces. I think this would have to be removed (possibly by arthroscope) prior to stem cell treatment to allow for these cells to exert their power....
Please forgive my rambling, I didn't mean to get so wordy with this...
01-30-2008, 10:46 PM
I posted about Regenerative Sciences on 11/9/07. It is post #1 under Other Issues and Diseases also Treated with Stem Cells. There are a couple of other useful things you can use on this forum. One is the search function. I put in what I am looking for (Regenerative Sciences in this instance) and I usually click on posts, not threads. It brings up the posts that have been made about this company. You will be notified automatically any time that you start a thread and someone replies to that thread. You can also view all of the day's posts by clicking on Today's Posts on the Home Page if you are not logged in. If you are logged in, it will say New Posts. You can only reply to a post if you are logged in. As for me, I have given several updates in the pulmonary section and I have also co authored a book with my stem cell mate, Jeannine that details our progress. I continue to feel better although I have had my ups and downs. I am thankfully in the mostly ups at this point. It was a very simple process for me. An IV in the arm that took less than 30 minutes. I did have an adverse reaction and thought I had just bought the farm, but I recovered quickly and later learned that that can happen even to big burly football players. Thank you for your nice comments.
By the way, ramble all you want. This forum is for stem cell discussion and many of us are very interested in all facets of it and the way it is used to treat various diseases. Describing what you have is a way that we can understand what is going on with you. I appreciate that. I think a phone call is warranted since they did not get back to you promptly. Like I said, they were very gracious when I called, so I would hope you would get the same response if you call.
01-31-2008, 01:20 PM
May I inquire as to the nature of your adverse reaction? Evidently your protocol involved systemic application vice local or site application. Were these cells from your own system? I'd be very interested in your book; please provide me as to how I can buy it...
01-31-2008, 04:08 PM
I think my reaction had more to do with my immune system than anything else. I had umbilical cord stem cells in an IV in my arm and it was a very simple, less than 30 minute procedure. Very few have this reaction, but it does occur. I didn't know that and wished I had. The doctor attending me was right on the spot to give me some adrenaline as my blood pressure had dropped. I got very hot and felt weak and unable to get my breath like a major asthma attack or something. We would love to have you buy a book. It benefits the forum and a fund we are establishing to try to help people who do not have the funds for the full cost of treatment. You may purchase one via our forum (click on the large banner on the Home Page that says BUY It HERE or click on the word store) or you can purchase it on Amazon if you wish. You will get to read all about our Pioneer adventures.
01-31-2008, 06:06 PM
Thank you so much; I just bought the book; please alow me to add, I can only try to imagine what you and your close friend have gone through in your desperate and probably frantic search for a way out; and that goes for all of us who find ourselves caught in one or another monstrous circumstance.
These experiences have a strong tendency to have profound effects on our compassion/sympathy/empathy toward others who fall prey to vicious whims of chance...I know my dilemma has had that effect on me...
01-31-2008, 07:03 PM
Jeannine and I thank you for your book purchase. Yes, I can truly say my entire life has been changed not just from my disease, but from everything that has happened to me in my quest for a cure. Along, the way I have sure met some nice people. Did you call the Colorado clinic yet? I hope you will let us know what they say. I should remind everyone that the books are shipped media mail and can take up to 7-10 days to receive in the U.S. They have been known to get there much faster especially since we use the extra 4 digits on the zip codes. That really does seem to help. All books are shipped within 24 hours of receipt of order. If you like our book, please let us know. If you don't, please don't say anything. HA Just joking, although as a moderator I do have the ability to edit posts.
02-01-2008, 02:44 PM
I like the way you put it "vicious whims". I call them personal disasters.
I have a developmentaly disabled daughter so I've been far more compassionate towards others misfortunes since she was born almost 35 years ago.
02-04-2008, 12:25 PM
My discovering this Web site has provided an enlightening experience; one I don't think I'll ever forget...
I did call Regenerative Sciences this morning; I had to leave a message vice talking to anyone there...I do hope they call back! I filled out their "Candidate Questionaire" about a week ago, but never got a response to that.
And Jeannine, you are correct; my use of the term "vicious whim" was my euphemism for 'personal disaster", that's for sure....
In the event I am able to talk with Regenexx, I'll certainly report any details to this group....My intent is to try to set up a consultation, along with providing X-rays, MRIs, etc....
02-04-2008, 01:19 PM
I have been diagnosed with Degenerative Disk Disease in my Cervical Spine recently and have tried the therapy and have seen the surgical specialist. I have talked to and know several people who have taken the surgical route and are more than dissatisfied. I have been searching the web for stem cell therapy for the disease i have and it is pretty much non-existing. However, I did find a clinic out of California that said they could possibly help me with stem cell therapy in Mexico. It is so hard to take the LEAP, but with the level of degeneration that i have in my neck i cant see a surgical end to my problem. I see surgery after surgery, fusion after fusion with no real help.:eek: York was talking about a place in Colorado that may be doing some stem cell therapy, as i too am from Colorado and only 125 miles from Denver i will have to get their phone number and set up an appointment for a consultation. If ANYONE has any answers for me please call me at 970 522 4384 or 970 886 3993 in evening my name is Paul L. Thank You !
02-04-2008, 03:52 PM
Paul - There are several posts dating back to November on the Colorado clinic. If you or Yorkere have any trouble whatsoever receiving a call back or information from the clinic, please tell me and I will drive there and see why you aren't getting your calls returned in a timely manner. I suspect that this clinic is doing very well, but I know how anxious I was to receive information when I was looking for treatment, so the offer still stands for me to drive up and visit them. I'm glad that both of you found our forum!
Paul - I would go ahead and fill out the form for the clinic like Yorkere did. This way if they have a backlog, you will at least be on the list to get a call.
02-04-2008, 04:57 PM
Barbara, et al:
I spoke with a Regenerative Sciences rep this morning (her name is "k fulton", I can't remmber what her first name is!); I was advised to send in any X-rays and MRIs I had, along with a short summary, or recent history. Their doctor would review and they would provide an opinion as to whether we should continue.
In response to my question as to whether the Stem Cell treatment could induce the bone structure to re-model toward normal, she stated it probably would not; that the srem cells affect soft tissue such as cartilage and other stuff...I was advised that since I'd had injections of SynVisc (Hyaluronic acid) recently, that I would have to wait ~a month or so, since these injections lower inflammation and the stem cells need inflammation to work properly.
I'll mail my CDs in to them tomorrow morning and wait for their response.
I tried to find "biostemcell.com" on the "Net, but I only came up with some kind of a generic page! Can you provide a phone number for them? Many Thanks!
02-05-2008, 08:44 AM
This is the company that I recently contacted and they had some very good information they were able to offer me. The doctor called me exactly when they said they would. We talked infact for almost 1 1/2 hour and he answered eevery question i had. The phone number for this clinic is 1-877-stem 123. The company is in California but they do the stem cell injection either in mexico or the camen islands. If anyone has questions call and set up a conference with one of the doctors. I believe the web site is stemcellbiotherapy.com....... GOOD LUCK
02-05-2008, 11:16 AM
This company does a sponsor ad here on the forum. You can click on the icon on the Home Page that is to the left of the Puritan's Pride icon. They also give a discount to anyone seeking treatment there that is a Pioneer forum member. One of our members complained about this and the sponsor ads. I haven't heard of anyone else complaining about a discount. I am all for saving money personally. Any of the stem cell companies are worth trying to negotiate the price with. Why not try anyway?
02-06-2008, 08:11 AM
Just wanting to know if anyone has used them or knows of anyone who has used them and how they are doing
02-06-2008, 08:22 AM
Just wanting to know if anyone has used them or knows of anyone who has used them and how they are doing
barbara jeannine and a number of others on here have used the SCB clinic you talk about,and there are others who are going in the next few months, im hoping to go too im in touch with them now!
02-06-2008, 12:59 PM
I am currently in touch with them also. I just infact faxed the financial assistance form back to them in hopes of reducing the cost for me as i know i couldn't afford $25,000 with my income even with a 5 yr. plan. The SCB clinic does sound the most promissing though. Maybe we'll be taking the journey at the same time. My friend and his wife just got back from mexico, south of Yuma, Az. and she received hers for her lungs and ben was a bit upset with the clinic because at two different times during his " cleations " (?)
before he could get his stem cells for his diabetic condition they missed his vien and the fluid just ran into his arm. Needless to say he was quite upset as they kept telling him it was normal to have some stinging. He told me this morning that they harvest these stem cells from sheep. Maybe thats why the shots are $900.00 but he has to go back minimum of once a year as does his wife. Is that the difference between animal and human stem cells?
02-06-2008, 02:40 PM
Paul - Sheep cells are called live cell therapy. Many patients on this forum have had it, especially for COPD. It makes them feel very good at first, but unfortunately, it is not a long term solution as it wears off. Each time apparently, gives less and less improvement to the patient. It is only $900.00, but it is not stem cell therapy.
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